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…The use of an autologous bone plug to seal the intramedullary femoral canal has been shown to be effective in reducing postoperative bleeding…

…They observed that patients without a femoral bone plug required significantly more blood transfusions…

Ettore Vulcano, MD; Gianmarco M. V. Regazzola, MD; Luigi Murena, MD; Mario Ronga, MD; Paolo Cherubino, MD; Michele F. Surace, MD